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Medical Council of Canada MCCQE Part 1 Sample Questions:

1. A 35-year-old woman, gravida 3, para 0, aborta 3, presents with her male partner because she has been unable to conceive despite trying for more than 1 year. Her menstrual cycles have been absent for 9 months, and she has occasional mild cyclic pain. She has a medical history of 3 suction curettages. Her BMI is 24.
Investigation results are as follows:
Hysterosalpingogram: Obliterated uterine cavity, no tubal dye spill
Progesterone (midluteal): 48.0 nmol/L (16.4-59.0)
Partner's semen: All parameters normal
Which one of the following is the most likely diagnosis?

A) Intrauterine synechiae
B) Fibroids
C) Polycystic ovary syndrome
D) Hypothalamic insufficiency
E) Perimenopause

2. You are being consulted for a 79-year-old man who is about to undergo a total hip arthroplasty. His orthopedic surgeon is aware of the diagnosis of Alzheimer disease and would like your suggestions to help avoid acute postsurgical delirium. To that end, which one of the following is the most effective strategy?

A) Keep family visits to a minimum to avoid postsurgical overstimulation
B) Screen the patient with the Mini-Mental Status Examination prior to surgery
C) Refrain from prescribing opiate analgesics to treat postoperative pain
D) Avoid medications with anticholinergic potential
E) Treat postsurgical insomnia with benzodiazepines

3. A 37-year-old man comes to the office for follow-up of his opioid use disorder. He receives opioid agonist treatment, including some take-home doses. At this follow-up visit, he reports some nonprescription opioid use since his last visit. Which one of the following is the best next step?

A) Prescribe a cannabinoid
B) Discontinue take-home doses
C) Increase the frequency of follow-up visits
D) Slowly taper and discontinue the opioid agonist
E) Taper the dosage of the opioid agonist

4. A patient's mother comes to you with a prospective cohort study linking autism to the measles, mumps and rubella vaccine. After reviewing the study carefully, you question the results because of problems with the study design and execution. Which one of the following sources of error would be most important in the study design or execution?

A) Reporting standard error with point estimates of difference
B) Parental recall of vaccine administration
C) Recruitment of study families at an autism seminar
D) Not accounting for all potential confounders during recruitment
E) Vaccine company sponsorship of study

5. A 29-year-old woman, gravida 1, para 0, aborta 0, presents to your clinic. Her pregnancy is at 22 weeks' gestation. Her blood pressure is 158/96 mm Hg. Which one of the following antihypertensive medications is contraindicated for this patient?

A) Labetalol
B) Methyldopa
C) Ramipril
D) Nifedipine
E) Hydralazine

Solutions: